SmithRx is Transforming Pharmacy Benefits

We dedicated to reducing the complexity and costs of pharmacy benefits through radical transparency and cutting-edge technology.

Meet Our Leadership

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Securing the Lowest Cost Prescription Drugs

Our mission at SmithRx is to deliver affordable medications while upholding transparency and integrity, always prioritizing the best interests of both employers and patients.

Jake’s Personal Journey

To understand SmithRx is to understand the healthcare journey of its founder, Jake Frenz. His story is one that is deeply relatable to many Americans. At 22, Jake stepped into a caregiving role during his father’s battle with cancer. Soon after, he faced his own cancer diagnosis, one that threatened the amputation of his leg. Years later, he again navigated the complexities of managing specialty medications while caring for his mother during her long-term illness.

A Broken Benefits System

Jake’s personal experiences underscored the profound failings within the U.S. healthcare system, creating a deep connection to the struggles many face when trying to access necessary treatment.

Our Founding Philosophy

These systemic inefficiencies led Jake to establish SmithRx, with a mission to bring transparency and fairness to pharmacy benefits management—an area often defined by opacity and injustice. Today, that mission continues to drive a broader transformation toward equity, efficiency, and genuine human compassion in healthcare.

Our Values

At SmithRx, our guiding principles—Courage, Integrity, and Together—serve as our north star, shaping our culture, grounding our decisions, and fostering our partnerships.

Courage to Transform

We're not tinkering at the edges of a broken system. We're re-imagining what pharmacy benefits could be, and building a model where every incentive always points toward the lowest cost drug.

Courage to Transform

We're not tinkering at the edges of a broken system. We're re-imagining what pharmacy benefits could be, and building a model where every incentive always points toward the lowest cost drug.

Integrity to Lead

We believe honesty leads the way, and we hold ourselves to it first. Real transparency means clear data, no hidden fees, and turning a transaction into a partnership built to last.

Integrity to Lead

We believe honesty leads the way, and we hold ourselves to it first. Real transparency means clear data, no hidden fees, and turning a transaction into a partnership built to last.

Together to Succeed

Nothing this big gets created alone. We intentionally align with partners who share our purpose, moving forward together to make accessible, affordable care the new standard.

Together to Succeed

Nothing this big gets created alone. We intentionally align with partners who share our purpose, moving forward together to make accessible, affordable care the new standard.

SmithRx Continues to Fix Broken Pharmacy Benefits Management System, Closes $60M in Series C Funding Led by Venrock

Read about our most recent funding round and how we’re leveraging it to continue evolving the PBM system for the better.

SmithRx and Mark Cuban Cost Plus Drug Company Announce $9.5 Million in Client Savings Through Innovative Autoimmune Drug Sourcing

Through our partnership with Mark Cuban Cost Plus Drug Company, we reveal in Business Wire! Finance new savings data that showcases the power of the SmithRx approach to pharmacy benefits.

Drug pricing is broken. This San Francisco entrepreneur has a personal prescription

San Francisco’s leading business publication dives deep into CEO Jake Frenz’ personal passion for fixing drug pricing in America.

PBMs form Transparency-Rx to push for drug pricing reform

SmithRx is a founding member of Transparency-Rx, a lobbying coalition advocating for industry reforms targeting prescription drug costs. Learn more about our work in Modern Healthcare.

Why it's time for PBM rebates to come to an end

SmithRx CEO Jake Frenz opines in Fierce Healthcare on how a partisan government can join forces to combat rising drug prices.

Venrock leads pharmacy startup's $20m refill

Axios has the story on SmithRx’s 2022 Series B funding round, led by Venrock Partners.

SmithRx in the News

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