The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.

Welcome to SmithRx: Better Pharmacy Benefits

Route every prescription to the lowest net cost with clinical confidence.

The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.
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The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.
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The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

Legacy PBMs

These legacy models profit from complexity, hiding revenue in spreads and opaque pricing. While they may claim transparency, they often improve one client's rate by inflating costs for others. Typically owning their own pharmacies, these organizations face inherent conflicts of interest that prioritize their bottom line over employer savings.
These legacy models profit from complexity, hiding revenue in spreads and opaque pricing. While they may claim transparency, they often improve one client's rate by inflating costs for others. Typically owning their own pharmacies, these organizations face inherent conflicts of interest that prioritize their bottom line over employer savings.

Alternative PBMs

These "pass-through" models improve optics but continue to outsource care. While they may offer a friendlier interface or brand name, they frequently miss significant savings due to a lack of direct control over the pharmacy network. Without a unified platform to connect clinical and network logic, they remain reactive rather than proactive.
These "pass-through" models improve optics but continue to outsource care. While they may offer a friendlier interface or brand name, they frequently miss significant savings due to a lack of direct control over the pharmacy network. Without a unified platform to connect clinical and network logic, they remain reactive rather than proactive.

How DPE Works

How DPE Works

How DPE Works

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Drug Mix

Clinically-Guided Drug Selection
The Drug Pathways Engine intercepts applicable utilization management requirements, prompting clinical experts to coordinate switches to lowest-cost alternatives if clinically appropriate.

Savings Multipliers

Capture and Apply All Savings Opportunities
The Drug Pathways Engine triggers
program enrollment to capture savings opportunities and secures the lowest net cost for the member and their plan.

Pharmacy Network

Route to the Most Cost-Conscious Source
The Drug Pathways Engine scans our pharmacy network and directs members to the lowest-cost, most convenient option: anywhere from local pharmacies to 
mail-order.

How SmithRx is Built for You —
Not Just Different

How SmithRx is Built for You —
Not Just Different

How SmithRx is Built for You —
Not Just Different

Model

How It Works

Why it’s Broken

Why SmithRx Wins

Legacy PBMs

These PBMs retain rebates, set hidden spreads, and profit when costs rise.

Misaligned incentives, opaque pricing, minimal accountability.

DPE delivers real net cost optimization and full transparency.

Alternative PBMs

These PBMs have improved UI and reporting, but still depend on leased networks, third-party clinical vendors, or partial
pass-through models.

Fragmented execution; savings stop at identification.

SmithRx owns network, clinical, and support execution under one model, so savings actually happen.

Legacy PBMs

How It Works

These PBMs retain rebates, set hidden spreads, and profit when costs rise.

Why It’s Broken

Misaligned incentives, opaque pricing, minimal accountability.

Why SmithRx Wins

DPE delivers real net cost optimization and full transparency.

Alternative PBMs

How It Works

These PBMs have improved UI and reporting, but still depend on leased networks, third-party clinical vendors, or partial 

pass-through models.

Why It’s Broken

Fragmented execution; savings stop at identification.

Why SmithRx Wins

SmithRx owns network, clinical, and support execution under one model, so savings 

actually happen.

Results You Can See

We eliminate the complexity and drive down the cost of pharmacy benefits for every client. The result? Realized plan savings and positive member experiences.

20

%+

%+

%+

Average client savings on pharmacy benefits*
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.

*Based on 2025 claims data and industry benchmarks

$

$

$

37

Average PMPM savings*

*Based on 2025 data across all SmithRx clients. Individual savings by group and member may vary.

97

%

%

%

Client retention rate as of 2025
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.

4.5/5

Member satisfaction score*

*Based on 2025 member surveys

See Your Pharmacy Benefit Through the Drug Pathways Engine

Experience how real transparency and execution work together to reduce costs—without compromising care.

SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 11am - 4pm ET

© 2026 Smith Health, Inc
SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 11am - 4pm ET

© 2026 Smith Health, Inc
SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 11am - 4pm ET

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© 2026 Smith Health, Inc