The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.
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Welcome to SmithRx: Better Pharmacy Benefits

Route every prescription to the lowest net cost with clinical confidence.
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The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.
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The SmithRx Drug Pathways Engine

Route every prescription to the lowest net cost with clinical confidence.
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The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

The Problem with “PBM Innovation”

The PBM industry is crowded with claims of transparency and technology, but most models still rely on the same underlying economics.

Legacy PBMs

These legacy models profit from complexity, hiding revenue in spreads and opaque pricing. While they may claim transparency, they often improve one client's rate by inflating costs for others. Typically owning their own pharmacies, these organizations face inherent conflicts of interest that prioritize their bottom line over employer savings.
These legacy models profit from complexity, hiding revenue in spreads and opaque pricing. While they may claim transparency, they often improve one client's rate by inflating costs for others. Typically owning their own pharmacies, these organizations face inherent conflicts of interest that prioritize their bottom line over employer savings.

Alternative PBMs

These "pass-through" models improve optics but continue to outsource care. While they may offer a friendlier interface or brand name, they frequently miss significant savings due to a lack of direct control over the pharmacy network. Without a unified platform to connect clinical and network logic, they remain reactive rather than proactive.
These "pass-through" models improve optics but continue to outsource care. While they may offer a friendlier interface or brand name, they frequently miss significant savings due to a lack of direct control over the pharmacy network. Without a unified platform to connect clinical and network logic, they remain reactive rather than proactive.

How DPE Works

Three layers of intelligence, zero missed opportunities. 

How DPE Works

Three layers of intelligence, zero missed opportunities. 

How DPE Works

Three layers of intelligence, zero missed opportunities. 

How DPE Works

Three layers of intelligence, zero missed opportunities. 
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Clinical Logic

Identifies lower-cost, clinically appropriate alternatives.

Network Logic

Agnostically recommends optimal site of fill by comparing an pharmacy options and pricing.

Pricing Logic

Factors in rebates, assistance programs, and network discounts without artificial inflation.

Execution Ethos

Our in-house patient advocates guide complex transitions end-to-end to ensure a smooth member experience and that savings are realized.

How SmithRx is Built for You —
Not Just Different

How SmithRx is Built for You —
Not Just Different

How SmithRx is Built for You —
Not Just Different

How SmithRx is Built for You —
Not Just Different

Model

How It Works

Why it’s Broken

Why SmithRx Wins

Legacy PBMs

These PBMs retain rebates, set hidden spreads, and profit when costs rise.

Misaligned incentives, opaque pricing, minimal accountability.

DPE delivers real net cost optimization and full transparency.

Alternative PBMs

These PBMs have improved UI and reporting, but still depend on leased networks, third-party clinical vendors, or partial
pass-through models.

Fragmented execution; savings stop at identification.

SmithRx owns network, clinical, and support execution under one model, so savings actually happen.

Legacy PBMs

How It Works

These PBMs retain rebates, set hidden spreads, and profit when costs rise.

Why It’s Broken

Misaligned incentives, opaque pricing, minimal accountability.

Why SmithRx Wins

DPE delivers real net cost optimization and full transparency.

Alternative PBMs

How It Works

These PBMs have improved UI and reporting, but still depend on leased networks, third-party clinical vendors, or partial 

pass-through models.

Why It’s Broken

Fragmented execution; savings stop at identification.

Why SmithRx Wins

SmithRx owns network, clinical, and support execution under one model, so savings 

actually happen.

Results You Can See

We eliminate the complexity and drive down the cost of pharmacy benefits for every client. The result? Realized plan savings and positive member experiences.

20

%

%

%

%

average client savings within the first plan year*
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.

*Based on 2025 claims data and industry benchmarks

$

$

$

$

26

reduction in PMPM*

*2024 Calendar Year

98

%

%

%

%

member satisfaction with clinical transitions
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.

100

%

%

%

%

of rebates and discounts passed through
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.
Portal access, data insights, and tools to deliver smarter benefits solutions.

Built for Every Stakeholder

Built for Every Stakeholder

Built for Every Stakeholder

Built for Every Stakeholder

See Your Pharmacy Benefit Through the Drug Pathways Engine

Experience how real transparency and execution work together to reduce costs—without compromising care.

SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

© 2025 Smith Health, Inc
SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

© 2025 Smith Health, Inc
SmithRx Logo

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

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© 2025 Smith Health, Inc