Every Claim. Its Lowest Net Cost. Every Time.

A Drug Pathway is the optimal route to the lowest net cost on every drug, for every member, on every claim.

Video poster

Every Claim. Its Lowest Net Cost. Every Time.

A Drug Pathway is the optimal route to the lowest net cost on every drug, for every member, on every claim.

Video poster

Every Claim. Its Lowest Net Cost. Every Time.

A Drug Pathway is the optimal route to the lowest net cost on every drug, for every member, on every claim.

Video poster

Three Dimensions. One Goal.

Every drug claim runs through all three dimensions simultaneously—not as a checklist, but as a single, continuous optimization.

Three Dimensions. One Goal.

Every drug claim runs through all three dimensions simultaneously—not as a checklist, but as a single, continuous optimization.

Three Dimensions. One Goal.

Every drug claim runs through all three dimensions simultaneously—not as a checklist, but as a single, continuous optimization.

The Right Drug
SmithRx evaluates every claim against clinically equivalent alternatives to find the lowest net cost option that works for the member.
The Right Drug
The Right Place
The Right Price
The Right Drug

How it Works: Meet the Drug Pathways Engine

A new generation of PBMs gave employers more visibility into drug spend. SmithRx built them an engine. One that identifies and routes every claim to the lowest net cost pathway, automatically.

How it Works: Meet the Drug Pathways Engine

A new generation of PBMs gave employers more visibility into drug spend. SmithRx built them an engine. One that identifies and routes every claim to the lowest net cost pathway, automatically.

How it Works: Meet the Drug Pathways Engine

A new generation of PBMs gave employers more visibility into drug spend. SmithRx built them an engine. One that identifies and routes every claim to the lowest net cost pathway, automatically.

Discovery

The Drug Pathways Engine continuously identifies the lowest net cost pathway available for every drug, across every dimension.

Discovery

The Drug Pathways Engine continuously identifies the lowest net cost pathway available for every drug, across every dimension.

Routing

At the point of claim, the engine routes the member to the optimal pathway: the right drug, the right source, the right savings opportunities.

Routing

At the point of claim, the engine routes the member to the optimal pathway: the right drug, the right source, the right savings opportunities.

Execution

Drug pathways are carried out through multiple methods—such as automatic, clinical, and point-of-sale—with new approaches continuously being developed as the market evolves.

Drug Pathway Example: Weight Management

drugs

Zepbound
Wegovy

$11,700/year

post rebates

right drug

Drug Selection

Low-list price GLP-1s

Prescribed by

Weight Management Partner

right PLACE

Drug Source

Lilly/Direct

designated pharmacy

28-day supply

right PRIce

Cost Modifiers

Plan cost

$349 or less/month

Member copay

$100/month

savings

50%
savings per fill

$5,850/year

wrap around support

Clinical Care

$81/month

fee per member

The Numbers Speak for Themselves

Every dollar of savings is real, reported, and traceable to a specific pathway decision.

The Numbers Speak for Themselves

Every dollar of savings is real, reported, and traceable to a specific pathway decision.

The Numbers Speak for Themselves

Every dollar of savings is real, reported, and traceable to a specific pathway decision.

20%+

Per Member Per Month Savings

Lower PMPM than the industry benchmark

$320M

Total 2025 Pathway Savings

$37

Average PMPM 2025 Pathways Savings

Built for Every Stakeholder

Built for Every Stakeholder

For Employers

Lower total pharmacy spend, access full data ownership, get measurable ROI.

For Employers

Lower total pharmacy spend, access full data ownership, get measurable ROI.

For Brokers & Consultants

Fiduciary alignment you can trust—and a model that’s easy to explain.

For Brokers & Consultants

Fiduciary alignment you can trust—and a model that’s easy to explain.

For Members

Lower out-of-pocket costs and real human support that ensures continuity of care.

For Members

Lower out-of-pocket costs and real human support that ensures continuity of care.

See Your Pharmacy Benefit Through the Drug Pathways Engine

Experience how real transparency and execution work together to reduce costs—without compromising care.

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 9am - 7pm ET

© 2026 Smith Health, Inc

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 9am - 7pm ET

© 2026 Smith Health, Inc

SmithRx is on a mission to reduce the complexity and costs of pharmacy benefits with radical transparency and cutting-edge technology.

Pharmacy and Provider Line
Member Help

M-F 8am - 9pm ET; Saturday 9am - 7pm ET

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© 2026 Smith Health, Inc